DIAGNOSTIC TECHNIQUE OF PREECLAMPSIA IN PREGNANT WOMEN WITH CHRONIC ARTERIAL HYPERTENSION

摘要

FIELD: medicine.;SUBSTANCE: what is presented is a diagnostic technique for preeclampsia in a pregnant woman with chronic arterial hypertension on her 24-40 weeks of pregnancy. Using ELISA, blood serum is examined for the content of IgG autoantibodies against duplex DNA, thrombocyte membrane antigens TrM-001-15 and TrM-015-12, renal tissue antigens KiM-05-300 and KiS-07-120 and liver mitochondrial antigen NMMR. Further, each value of the examined antibodies is described for the autoantibodies ratio in the test serum to the control serum. If the value is 0.55 or less of at least three types of the autoantibodies, one of which refers to the antibodies in kidney tissue, and the other - to the duplex DNA, preeclampsia is diagnosed in the pregnant woman.;EFFECT: invention provides the effective diagnostic technique for preeclampsia in pregnant women with chronic arterial hypertension on their 24-40 weeks, and the improvement of the perinatal outcomes.;2 ex