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With dendritic poly glycerol sulfate functionalized nanoparticles

机译:用树枝状聚甘油硫酸酯官能化的纳米颗粒

摘要

The present invention relates to nanoparticles, characterized bya) a core of an inorganic material andb) an envelope of the left and the dendritic poly glycerol sulfate,wherein the poly glycerol sulfate from repeating glycerol - units of the formula (ro - ch2)2Ch - or, where r = h, or further glycerol - units, one or of a plurality of oh - groups of the glycerol - units by sulfate - groups of the formula - oso3X, wherein x is h, an alkali metal atom, such as li, na or k, or an ammonium ion are replaced,and wherein the linker poly glycerol sulfate and the core connects to one another.The nanoparticles are suitable for medical applications, for example for the diagnosis and treatment of inflammatory diseases.
机译:本发明涉及纳米粒子,其特征在于:a)无机材料的芯和b)左侧和树突状聚甘油硫酸盐的包膜,其中由重复的甘油-式(ro-ch 2 2 Ch-或(其中r = h时)或其他甘油-单元,甘油中的多个OH-单元中的一个或多个-硫酸根单元-下式-oso 3 X,其中x为h,替换诸如li,na或k的碱金属原子或铵离子,并且其中连接基聚硫酸甘油酯和核心连接一个纳米颗粒适用于医学应用,例如用于炎症性疾病的诊断和治疗。

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