PLASMA BIOMARKER TOOL FOR DIAGNOSIS OF LIVER CANCER COMPRISING LIVER CARBOXYLESTERASE 1 AND LIVER CANCER SCREENING METHOD

摘要

PROBLEM TO BE SOLVED: To provide a new diagnostic biomarker containing human liver carboxylesterase 1 which can effectively discriminate liver cancer patients based on plasma.;SOLUTION: The present invention relates to a plasma biomarker for diagnosing liver cancer, and to discovery of a protein in plasma that has not been reported, using proteomics techniques such as 2-D fluorescence gel electrophoresis, immunoprecipitation, and a nano-liquid chromatography mass spectrometry system. By demonstrating the presence of a protein marker of the invention in plasma and confirming that its expression level is higher in plasma of liver cancer patients than of healthy volunteers, this invention may be used in a liver cancer diagnosing and screening method.;COPYRIGHT: (C)2015,JPO&INPIT