首页>
外国专利>
Methods for reducing the possibility of thromboembolism of plasma-derived immunoglobulin compositions
Methods for reducing the possibility of thromboembolism of plasma-derived immunoglobulin compositions
展开▼
机译:降低血浆源性免疫球蛋白组合物血栓栓塞可能性的方法
展开▼
页面导航
摘要
著录项
相似文献
摘要
The present invention provides methods for reducing the amidolytic and anti-complement activity (ACA) content of an immunoglobulin composition through the use of cation exchange chromatography. In a specific embodiment, the invention provides methods for reducing the Factor XI and/or Factor XIa and/or ACA content of an immunoglobulin composition by collecting the leading portion of a cation exchange eluate. The present invention also provides immunoglobulin composition having reduced levels of amidolytic activity, Factor XI, and/or Factor XIa, and/or ACA content.
展开▼