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Use of DTBZ to image pancreatic endocrine and beta cell populations in type 1 diabetes

机译:使用DTBZ成像1型糖尿病的胰腺内分泌和β细胞数量

摘要

This invention in the pancreas of the non invasive object, being the method of deciding the cell population, the process which prescribes the vesicular mono amine trance porter 2 type (VMAT2) - unique radioactive ligand of the effective quantity to the aforementioned object; Concerning at least the portion of the pancreas of the aforementioned object, the process which at least acquires the computer conversion picture of 1; And, in the pancreas of the aforementioned object, in order that the cell population is decided, including the process which it measures analyzes the aforementioned computer conversion picture, it offers the method of becoming. In addition, as for this invention, the method of diagnosing nervous incretion obstacle such as insurinoma, diabetes, and the front clinical diabetes in the metabolism object, and the method of deciding the disposal efficiency of metabolism obstacle are offered. Furthermore, this invention diabetes offers the method of managing the disposal or prevention of method, and the diabetes which appraise the convalescence of the object which has the fear of emerging. In addition, this invention in the pancreas of the object, the kit which is used for the diagnosis of metabolism obstacle or nervous incretion obstacle of decision, and the object of the cell population is offered. Selective figure It is not
机译:在非侵入性对象的胰腺中,本发明是确定细胞数量的方法,该方法规定了水泡单胺tr搬运剂2型(VMAT2)-有效量的上述对象的独特放射性配体;关于上述对象的胰腺的至少一部分,至少获取1的计算机转换图像的处理。并且,在上述对象的胰腺中,为了决定细胞群,包括对其进行测定的过程进行分析上述计算机转换图像,从而提供了成为一种方法。另外,对于本发明,提供了诊断代谢对象中的保险瘤,糖尿病和前临床糖尿病等神经增量障碍的方法,以及确定代谢障碍的处置效率的方法。进而,本发明的糖尿病提供治疗方法的预防或方法的预防的方法,以及提供对有可能出现的对象的恢复性进行评价的糖尿病。另外,本发明提供了对象的胰腺,用于诊断代谢障碍或决定性神经增量障碍的试剂盒以及细胞群的对象。

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