Multiplex detection of tumor cells using a panel of agents that bind to extracellular markers

摘要

The present invention relates to a one step method for detection of a cancer cell or cancer cell element in a biological sample in sentinel nodes, metinel nodes, or other lymph nodes wherein the biological sample comprises a panel of labelled agents binding to two or more different extracellular markers wherein at least one agent binds to a cancer-type specific or cancer-subtype specific extracellular marker and wherein at least one further agent binds to a tissue-specific extracellular marker.