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AUTOMATED MRI DETECTION OF TISSUE MACROMOLECULAR T2/T2* CHARACTERISTICS USING Z-SPECTRA
AUTOMATED MRI DETECTION OF TISSUE MACROMOLECULAR T2/T2* CHARACTERISTICS USING Z-SPECTRA
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机译:使用Z-SPECTRA进行组织大分子T2 / T2 *特征的MRI自动检测
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摘要
A magnetic resonance imaging (MRI) system and method (a) acquires k-space data for a patient ROI over a predetermined band of RF frequencies using RF excitation pulses having respectively corresponding RF frequencies incrementally offset from a nuclear magnetic resonant (NMR) Larmor frequency for free nuclei thus causing chemical exchange saturation transfer (CEST) effects and to process such acquired data into Z-spectra data for voxels in the ROI; (b) analyzes the acquired Z-spectra data to provide spectral peak width data corresponding to T2/T2* tissue values in the ROI for macromolecules participating in magnetization transfer contrast (MTC) effects producing said Z-spectra data; and (c) stores and/or displays data representative of T2/T2* tissue values of the ROI which values are different for different tissues.
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