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Diagnostic Kit as Well as a Metho dfor the Examination of a Human Patient Sample for the Presence of Neuromyelitis Optica-Specific Antibodies
Diagnostic Kit as Well as a Metho dfor the Examination of a Human Patient Sample for the Presence of Neuromyelitis Optica-Specific Antibodies
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机译:诊断试剂盒以及用于检查人类患者样本中是否存在视神经脊髓炎特异性抗体的方法
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摘要
A diagnostic kit as well as a method for the examination of a human patient sample for the presence of neuromyelitis optica-specific antibodies are described, for which an initial substrate is incubated with human sample material, and said incubated initial substrate is examined using indirect immunofluorescence, whether neuromyelitis optica-specific antibodies have at least partially bound to said initial substrate.;The solution described is characterized in that as said initial substrate, an aquaporin-4-containing native substrate is used as well as that said neuromyelitis optica-specific antibodies at least partially bound to said aquaporin-4-containing initial substrate are reacted with components of the complement system and the reaction of said complement system is detected by way of an indicator reaction.
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