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Use of a ghrelin agonist to improve the catabolic effects of glucocorticoid treatment
Use of a ghrelin agonist to improve the catabolic effects of glucocorticoid treatment
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机译:生长激素释放肽激动剂的使用,以改善糖皮质激素治疗的分解代谢作用
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摘要
A method and pharmaceutical composition for inhibiting the effect of glucocorticoids, particularly dexamethasone, which suppress growth hormone secretion, by administering ghrelin or a ghrelin analogue, for example, H-Inp-D-Bal-D-Trp-Phe-Apc-NH2 (SEQ ID NO:73) or other suitable ghrelin agonist, to counteract the catabolic effects of dexamethasone and other natural glucocorticoids.
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机译:通过施用生长素释放肽或生长素释放肽类似物(例如H-Inp-D-Bal-D-Trp-Phe-Apc-NH <)抑制糖皮质激素,特别是地塞米松的抑制生长激素分泌的作用的方法和药物组合物Sub> 2 Sub>(SEQ ID NO:73)或其他合适的生长素释放肽激动剂,以抵消地塞米松和其他天然糖皮质激素的分解代谢作用。
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