首页> 外国专利> COMPOUND, COMPOUND OR SALT THEREOF, PHARMACEUTICAL COMPOSITION, GLYCORTICOID RECEIVER MODULATOR, METHOD FOR PREVENTION AND / OR TREATMENT OF METABOLIC DISEASES, INFLAMMATORY DISEASES, NURSES, ALPHERE CARE DISEASES WITH HOMEOSTASE OR GLAUCOMA, AND USE AT LEAST ONE COMPOUND OR SALT OF THE SAME

COMPOUND, COMPOUND OR SALT THEREOF, PHARMACEUTICAL COMPOSITION, GLYCORTICOID RECEIVER MODULATOR, METHOD FOR PREVENTION AND / OR TREATMENT OF METABOLIC DISEASES, INFLAMMATORY DISEASES, NURSES, ALPHERE CARE DISEASES WITH HOMEOSTASE OR GLAUCOMA, AND USE AT LEAST ONE COMPOUND OR SALT OF THE SAME

机译:化合物,化合物或盐,药物组合物,糖皮质激素受体调节剂,预防和/或治疗代谢性疾病,炎症性疾病,营养不良,荷尔蒙病或结节的青光眼和结石的治疗和/或治疗方法

摘要

The compounds represented in general formula (1) or a salt thereof are useful for glucocorticoid receptor modulators. In the formula, R 1 represents a lower alkyl group, a lower cycloalkyl group, an aryl group and the like; R 2 represents a hydrogen atom, a lower alkyl group and the like; R 3 represents a hydrogen atom, a lower alkyl group and the like; R 4 and R 5 represent a hydrogen atom, a lower alkyl group and the like; R 6 represents a hydrogen atom, a lower alkyl group and the like; R 7 represents a hydrogen atom, a lower alkyl group, a lower alkenyl group and the like; W represents an oxygen atom, a sulfur atom, NR 8 and the like; R 8 represents a hydrogen atom, a lower alkyl group and the like; X represents an oxygen atom or a sulfur atom; Y represents a lower alkylene group and the like; Z represents an oxygen atom, a sulfur atom, NR 9 , OCO or OSO 2 ; R 9 represents a hydrogen atom, a lower alkyl group and the like respectively.
机译:通式(1)表示的化合物或其盐可用于糖皮质激素受体调节剂。式中,R 1表示低级烷基,低级环烷基,芳基等。 R 2表示氢原子,低级烷基等。 R 3表示氢原子,低级烷基等。 R 4和R 5表示氢原子,低级烷基等。 R 6表示氢原子,低级烷基等。 R 7表示氢原子,低级烷基,低级烯基等。 W表示氧原子,硫原子,NR 8等。 R 8表示氢原子,低级烷基等。 X表示氧原子或硫原子; Y表示低级亚烷基等。 Z表示氧原子,硫原子,NR 9,OCO或OSO 2; R 9分别表示氢原子,低级烷基等。

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