The present meaning is 2.

摘要

Provide the original cytokine, defined as this delta_-2, induced apoptosis of tumor cells in mammals. He is considered to be a member of the -2 family of TNF cytokines. A nucleic acid binding region including a ligand of the chimera-2 of the composition, the coding 2, and the binding region of the antibody, Nong-2, are also provided.This method provides additional ligand 2 - induced conditions for apoptosis and treatment of diseases, such as cancer.