首页> 外国专利> METHODS FOR THE TREATMENT OF ALCOHOL INTOXICATION, DISORDERS RELATED TO THE USE OF ALCOHOL, AND ABUSE OF ALCOHOL, THAT INCLUDE THE INTRODUCTION OF DIHYDROMYRICETIN

METHODS FOR THE TREATMENT OF ALCOHOL INTOXICATION, DISORDERS RELATED TO THE USE OF ALCOHOL, AND ABUSE OF ALCOHOL, THAT INCLUDE THE INTRODUCTION OF DIHYDROMYRICETIN

机译:治疗酒精中毒的方法,与使用酒精有关的疾病和滥用酒精,其中包括引入二氢缩水甘油

摘要

Disclosed herein are methods for treating alcohol intoxication, alcohol-related disorders, and alcohol abuse, which include administering dihydromyretin. As described herein, dihydromyreticin potentiates the activity of GABAR with the alpha4-beta delta subunit, which is associated with the effects of ethanol, counteracts the action of ethanol on GABAR, acts on the benzodiazepine sites of GABAR and inhibits, reduces and / or reverses the plasticity of some or all of GABAR, which due to exposure to ethanol.
机译:本文公开了用于治疗酒精中毒,酒精相关疾病和酒精滥用的方法,包括施用二氢髓磷脂。如本文中所述,二氢myreticin增强了具有α4-βδ亚基的GABAR的活性,其与乙醇的作用有关,抵消了乙醇对GABAR的作用,作用于GABAR的苯并二氮杂位并抑制,降低和/或逆转。由于暴露于乙醇而导致的部分或全部GABAR的可塑性。

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