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Genetically modified vesicular stomatitis virus (vsv), vectors comprising the same and immunogenic compositions thereof
Genetically modified vesicular stomatitis virus (vsv), vectors comprising the same and immunogenic compositions thereof
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机译:转基因的水疱性口炎病毒(vsv),包含其的载体及其免疫原性组合物
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摘要
The present invention broadly relates to the synergistic attenuation of vesicular stomatitis virus (VSV). More particularly, the invention relates to the identification of combined mutation classes which synergistically attenuate the pathogenicity of VSV vectors in mammals and immunogenic compositions thereof.
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