EXTRACTS OF PITHECELLOBIUM DULCE (BENTH) FRUIT PEEL AND USE THEREOF AS ANTI-DIABETIC FORMULATION

摘要

The present invention relates to an herbal formulation for the treatment and control of diabetes and associated complications, and comprising of extracts from selected Indian medicinal herbs which are proven to be safe and non-toxic, particularly comprising of standardized extracts of the plant Pithecellobium dulce (Benth) fruit peel, Syzygium cumini {Myrtaceae) seed and Aloe barbadensis (Liliaceae) sap. The extracts showed significant antidiabetic activity assessed by in-vitro a- amylase inhibition and in-vivo animal model. The extract of Pithecellobium dulce fruit peel contains pinitol a non-toxic molecule mimetic insulin activity and control the blood glucose level in diabetic animal. The herbal formulation comprising Pithecellobium dulce fruit peel containing pinitol as the major component and thus exhibit good antidiabetic activity.