Dual function in vitro target binding assay for the detection of neutralizing antibodies against target antibodies

摘要

An in vitro assay method is disclosed. This non cell based dual function target binding assay is useful for detecting both an IgG target antibody such as a biologic drug in a biological sample (e.g. a serum sample) and the presence of neutralizing antibodies (NAb) against the IgG target antibody.