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Otamixaban for treatment of elderly and renal impaired non-st elevation myocardial infarction patients
Otamixaban for treatment of elderly and renal impaired non-st elevation myocardial infarction patients
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机译:Otamixaban治疗老年和肾功能不全的非心肌梗死患者
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597957 Disclosed is the use of (2R,3R)-2-(3-carbamimidoyl-benzyl)-3-[4-(1-oxy-pyridin-4-yl) benzoylamino]-butyric acid methyl ester (otamixabin) or a pharmaceutically acceptable salt thereof, for the manufacture of a medicament for the treatment of non-STelevation myocardial infarction said treatment comprising administering (2R,3R)-2-(3-carbamimidoyl-benzyl)-3-[4-(1-oxypyridin-4-yl)benzoylamino]butyric acid methyl ester or a pharmaceutically acceptable salt thereof to a human patient, who is older than 65; more preferably over 75. Also disclosed is the use of (2R,3R)-2-(3-carbamimidoyl-benzyl)-3-[4-(1-oxy-pyridin-4-yl)Benzoylamino]-butyric acid methyl ester or a pharmaceutically acceptable salt thereof, for the manufacture of a medicament for the treatment of non-ST elevation myocardial infarction said treatment comprising administering (2R,3R)-2-(3-carbamimidoyl-benzyl)-3-[4-(1-oxypyridin-4-yl) benzoylamino]butyric acid methyl ester or a pharmaceutically acceptable salt thereof to a human patient, who shows renal insufficiency; more particularly they show renal insufficiency and a creatinine (creatinin) clearance from 50 millilitre per min to 80 millilitre per min.
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