METHOD FOR PERSONALIZED DOSING SCHEDULE FOR WARFARIN IN ANTICOAGULANT THERAPY

摘要

A method for the personalized dosing schedule for Warfarin in anticoagulant therapy comprises molecular genetic analysis. The allele variants *2 and *3 of CYP2C9 gene are detected. The presence of these non-functional alleles results in the reduced biotransformation of Warfarin necessitating the reduction of Warfarin doses.