首页> 外国专利> METHOD OF TREATMENT OF NEURODEGENERATIVE OR NEURO-MUSCULAR DEGENERATIVE DISEASES ANDTHERAPEUTIC AGENT TO TREAT THE SAME

METHOD OF TREATMENT OF NEURODEGENERATIVE OR NEURO-MUSCULAR DEGENERATIVE DISEASES ANDTHERAPEUTIC AGENT TO TREAT THE SAME

机译:神经退行性或神经肌肉退行性疾病的治疗方法以及治疗该疾病的疗法

摘要

Use of high doses above 1 gm per day of ascorbic acid or the derivatives thereof for the treatment of neurodegenerative and neuro-muscular degenerative diseases and disorders, in particular amytrophic lateral sclerosis, multiple sclerosis, alzheimer's disease, parkinson's disease, and muscular dystrophy is disclosed. Preferably the dose includes mannitol which facilitates the delivery of ascorbic acid to the target cells in the brain. Still further the said dose includes zinc citrate for preventing formation of kidney stones. Dose compositions for various routes of application such as oral, intravenous, intramuscular, nasal and in the form of transdermal patches are discussed.
机译:公开了每天使用高于1gm的高剂量抗坏血酸或其衍生物用于治疗神经变性和神经肌肉变性疾病和病症,特别是肌萎缩性侧索硬化,多发性硬化,阿尔茨海默氏病,帕金森氏病和肌营养不良症。 。优选地,该剂量包括甘露醇,其促进抗坏血酸向脑中靶细胞的递送。更进一步地,所述剂量包括柠檬酸锌以防止肾结石的形成。讨论了各种施用途径的剂量组合物,例如口服,静脉内,肌内,鼻内和透皮贴剂的形式。

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