Compositions comprising florfenicol or a compound structurally related to treat infection in cattle and pigs

摘要

A composition for the treatment of microbial infection in an animal comprising: a) only one active substance, consisting of the antibiotic of Formula I: wherein R is a member selected from the group consisting of methyl, ethyl or halogen derivative methyl or ethyl, dihalodeuteriometilo, 1-halo-1-deuterioethyl, 1,2-dihalo-1-deuterioethyl, azidomethyl and methylsulfonylmethyl; X and X 'is a member independently selected from the group consisting of NO2, SO2R1, SOR1, SR1, SONH2, SO2NH2, SONHR1, SO2NHR1, COR1, OR1, R1, CN, halogen, hydrogen, phenyl and phenyl mono-, di- or trisubstituted with halogen, NO2, R1, PO2R1, CONHR1, NHR1, NR1R2, CONR1R2, OCOR1, or OR1, wherein R1 and R2 are a member independently selected from the group consisting of methyl, ethyl, n-propyl, isopropilbutilo, t -butyl, isobutyl and phenyl; and Z is hydrogen or an acyl group of a hidrocarbonocarboxílico acid having up to 16 carbon atoms or an acyl group of a aminohidrocarbonocarboxílico acid having up to 12 carbon atoms; and pharmaceutically acceptable salts of said acyl groups; b) the vehicle triacetin. c) 2-pyrrolidone