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Favorable preparation for health and production method

机译:有利于健康的制备方法和生产方法

摘要

Method for producing a non-live lactobacillus preparation with specific binding capacity with Streptococcus mutans, which comprises the steps of: i) heating a suspension of cells of a lactobacillus or a mixture of lactobacilli, with specific binding capacity with Streptococcus mutans, in which case the specific binding a) is resistant to heat treatment and / or b) is resistant to treatment with protease and / or c) is dependent on calcium and / or d) takes place in a pH range between 4.5 and 8 , 5, and / or e) is carried out in the presence of saliva, from a starting temperature below 40 ° C to a pasteurization temperature of 75 to 85 ° C with a temperature change of 0.5 to 2 ° C / min, ii) keep the suspension heated at the pasteurization temperature for a period of 20 to 40 minutes, iii) cool the suspension obtained in step ii) to a final temperature below 40 ° C with a temperature change of 0.5 to 2 ° C / min
机译:生产与变形链球菌具有特异性结合能力的非活乳杆菌制剂的方法,该方法包括以下步骤:i)加热对变形链球菌具有特异性结合能力的乳杆菌或乳杆菌混合物的细胞悬液。特异性结合a)耐热处理和/或b)耐蛋白酶处理和/或c)依赖钙和/或d)在4.5至8、5和/的pH范围内发生或e)在唾液存在下进行,从起始温度低于40°C到巴氏灭菌温度为75至85°C,温度变化为0.5至2°C / min,ii)将悬浮液加热至巴氏灭菌温度持续20到40分钟,iii)将步骤ii)中获得的悬浮液冷却至40°C以下的最终温度,温度变化为0.5至2°C / min

著录项

  • 公开/公告号ES2497569T3

    专利类型

  • 公开/公告日2014-09-23

    原文格式PDF

  • 申请/专利权人 BASF SE;

    申请/专利号ES20100771064T

  • 发明设计人 COOPER BRYAN;

    申请日2010-10-11

  • 分类号A23L1/30;A61K8/99;A61K35/74;A61P1/02;A61Q11;C12R1/225;

  • 国家 ES

  • 入库时间 2022-08-21 15:55:02

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