SENSING MEMBRANE-BASED PLATFORM FOR TISSUE OR CELL CULTURING AND MONITORING

摘要

The present application discloses a tissue sample or cell culture sample monitoring assembly comprising a sensor assembly comprising a water-permeable sensor membrane consisting of a conducting polymer material defining an electrode of a thickness of 0.1-1,000 μm, and holding functionalizations specific to a certain cell tissue analyte, a metering device, conductor(s) electrically connecting the electrode of the sensor membrane with the metering device, and a tissue sample or a cell culture sample arranged on top of the sensor membrane of the sensor assembly, and a liquid medium receptacle wherein the sensor membrane and the tissue sample or the cell culture sample are arranged. A method of continuously or intermittently monitoring the concentration or presence of a tissue analyte in the proximity of a tissue sample or cell culture sample, a water-permeable sensor membrane and a sensor assembly are also disclosed.