AN OXIDATION PROCESS FOR THE PREPARATION OF N-3-AMINO-1- (CYCLOBUTYLMETHYL)-2,3-DIOXOPROPYL-3-{N-(TERT-BUTYLAMINO)CARBONYL-3-METHYL-L-VALYL}-6,6-DIMETHYL-3-AZABICYCLO3.1.0HEXANE-2-CARBOXAMIDE AND RELATED COMPOUNDS

摘要

The present application relates to a process for preparing a compound of formula I: wherein R1 is alkyl; R2 is alkyl; and R3 is optionally substituted cycloalklylalkyl which comprises oxidizing a compound of the formula wherein R1, R2 and R3 are defined above to yield a compound of formula I.