N‑SUBSTITUTED CHIRAL AROMATIC OXAZOLIDINES, SYNTHESIS PROCESS, PHARMACEUTICAL COMPOSITION AND USE

摘要

The present invention relates to the production of synthetic molecules of N‑substituted chiral aromatic oxazolidines, the process for the synthesis thereof, pharmaceutical compositions containing said molecules and to the use of these compositions, especially as anti‑tumour agents. The low‑molecular‑weight compounds obtained from the synthesis process promote the pharmacokinetic properties of the compositions and the efficacy of the therapy. These compounds further exhibit anti‑tumour activity, as observed in in‑vitro tests, against human tumour cell lines.