METHOD AND USE FOR VERIFICATION OF MOUNTING ERRORS IN GENOMES

摘要

The present invention relates to a method for verification of mounting errors in genomes of organisms, which genomes have been sequenced or produced synthetically, which utilizes frequency relationships between nucleotide sequence fragments of a genome. The method is of use in the verification of errors in a mounted genome based on fragments produced using different types of sequencing technology and assists in the construction of synthetic genomes, for example. The present invention may be used to compress genetic material since the frequency relationships determined by the method allow reduction of the nucleotide sequence complexity in such a manner as to represent the content thereof in compressed form, thereby reducing the space required for storage thereof.