FRACTIONAL ORDER AND ENTROPY BIO-MARKERS FOR BIOLOGICAL TISSUE IN DIFFUSION WEIGHTED MAGNETIC RESONANCE IMAGING

摘要

The invention disclosed herein provides an example method and system for characterizing a biological structure in terms of bio-markers derived from DWI data. The methodology includes estimating bio-markers in a fixed diffusion time protocol, estimating bio-markers in fixed diffusion encoding gradient strength protocol, calculating parameters of a model, and using the parameters to characterize a biological structure. Using the techniques and methods described herein, the data may be used to identify structural degeneration, structural integrity and response to therapeutics.