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Heterocyclic compounds as inhibitors of the sodium iodide symporter
Heterocyclic compounds as inhibitors of the sodium iodide symporter
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机译:杂环化合物作为碘化钠同向转运蛋白抑制剂
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摘要
The invention relates to new compounds of formula (I):for their use as medicaments, and in particular as inhibitors of sodium iodide symporter (NIS) and reducers of iodine transport and/or accumulation into NIS-expressing cells. The invention also relates to a pharmaceutical composition comprising at least one compound of formula (I) as active principle. Finally, the present invention relates to specific compounds of formula (I) as such.
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机译:本发明涉及式(I)的新化合物: <图像文件=“ IMGA0001.GIF” he =“ 58” imgContent =“ chem” imgFormat =“ GIF” wi =“ 63” /> Chemistry>用作药物,特别是用作碘化钠共转运蛋白(NIS)的抑制剂和碘转运和/或积累到NIS表达细胞中的碘的还原剂。本发明还涉及包含至少一种式(I)化合物作为活性成分的药物组合物。最后,本发明本身涉及式(I)的特定化合物。
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