首页> 外国专利> A COMPOSITION FOR TREATING DISEASES RELATED TO ANGIOGENESIS AND CORNEA OR CONJUNCTIVA TRANSPLANT USING CHONDROCYTE-DERIVED EXTRACELLULAR MATRIX MEMBRANE

A COMPOSITION FOR TREATING DISEASES RELATED TO ANGIOGENESIS AND CORNEA OR CONJUNCTIVA TRANSPLANT USING CHONDROCYTE-DERIVED EXTRACELLULAR MATRIX MEMBRANE

机译:用软骨细胞衍生的细胞外基质膜治疗与血管生成和角膜或结膜移植相关的疾病的组合物

摘要

The present invention provides a novel composition for treating angiogenic diseases using an extracellular matrix membrane of a cartilage-derived cell having a membrane or film form, which is excreted from cartilage cells that are cultured when the cartilage cells isolated from the cartilage of an animal is monolayer-cultured, and a transplant material for the cornea or the conjunctiva. The composition for treating the angiogenic diseases and the transplant material for the cornea or the conjunctiva, according to the present invention, suppresses endothelial cells from attaching or proliferating and impedes the movement of endothelial cells, thereby suppressing vascular endothelial growth and vascular penetration and thus ultimately suppressing angiogenesis. [Reference numerals] (AA) Matrigel; (BB) Matrigel / CD-ECM powder; (CC) Matrigel / Amnion powder
机译:本发明提供了一种新的组合物,其用于使用具有膜或膜形式的软骨衍生细胞的细胞外基质膜来治疗血管生成疾病,所述细胞外基质膜从当从动物软骨分离出的软骨细胞被培养时所培养的软骨细胞中排出。单层培养,以及用于角膜或结膜的移植材料。根据本发明,用于治疗血管生成疾病的组合物和用于角膜或结膜的移植材料抑制内皮细胞的附着或增殖并阻碍内皮细胞的运动,从而抑制血管内皮的生长和血管渗透,从而最终抑制血管内皮的生长和渗透。抑制血管生成。 [参考数字](AA)Matrigel; (BB)Matrigel / CD-ECM粉末; (CC)基质胶/羊膜粉

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