首页> 外国专利> A composition for treating diseases related to angiogenesis and cornea or conjunctiva transplant using chondrocyte-derived extracellular matrix membrane

A composition for treating diseases related to angiogenesis and cornea or conjunctiva transplant using chondrocyte-derived extracellular matrix membrane

机译:用软骨细胞衍生的细胞外基质膜治疗与血管生成和角膜或结膜移植有关的疾病的组合物

摘要

The present invention relates to a composition for treating a novel neovascular disease using a chondrocyte-derived extracellular matrix membrane formed in a membrane or a film form secreted from cultured chondrocytes when the cartilage cells isolated from animal cartilage are cultured as a monolayer, Provide the implant. The composition for treating a neovascular disease of the present invention and the cornea or conjunctival graft material inhibit vascular endothelial cell adhesion and proliferation and inhibit vascular endothelial cell migration, thereby inhibiting angiogenesis and vascular permeability, and ultimately inhibiting neovascularization.
机译:本发明涉及一种用于治疗新型新生血管疾病的组合物,其使用当从动物软骨分离的软骨细胞作为单层培养时,以软骨细胞来源的细胞外基质膜形成的膜或从培养的软骨细胞分泌的膜形式形成的软骨细胞外基质膜。 。本发明的用于治疗新血管疾病的组合物和角膜或结膜移植材料抑制血管内皮细胞的粘附和增殖并抑制血管内皮细胞的迁移,从而抑制血管生成和血管通透性,并最终抑制新血管形成。

著录项

  • 公开/公告号KR101539700B1

    专利类型

  • 公开/公告日2015-07-28

    原文格式PDF

  • 申请/专利权人

    申请/专利号KR20130106092

  • 申请日2013-09-04

  • 分类号A61K35/32;A61K35/12;A61P27/02;A61P35;

  • 国家 KR

  • 入库时间 2022-08-21 14:57:55

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