New Lactobacillus plantarum strain, the Method of isolating the strain and Composition for prevention and treation of colibacillosis using it

摘要

The present invention provides novel Lactobacillus plantarum strains which suppress E. coli diarrhea and a method for producing the same and relates to a pharmaceutical composition and a feed composition containing the same for preventing or treating E. coli diarrhea. A method for breeding lactic acid bacteria with enhanced antibacterial ability induces direct evolution compared with an existing mutation method of a nucleotide unit and generates various mutants in various characteristics, thereby producing Lactobacillus plantarum GS1 mutants with superior E. coli K99 resistance than wild type Lactobacillus plantarum. A composition containing the Lactobacillus plantarum strains is used as a pharmaceutical composition and a feed composition.