Method for gamma-aminobutyric acid with glycerol as substrate by biotransformation process

摘要

PURPOSE: A manufacturing method of gamma aminobutyric acid by biotransformation using glycerol as a substrate is provided to manufacture the gamma aminobutyric acid economically and eco-friendly since the glycerol produced as a by-product in biodiesel production is converted into high-priced gamma aminobutyric acid (GABA). CONSTITUTION: A method for manufacturing gamma aminobutyric acid (GABA) from glycerol using glutamate decarboxylase variant. Provided is a method of manufacturing the gamma aminobutyric acid (GABA) it is done by the substrate. The glutamate decarboxylase variant has an activity at a neutral pH. The glutamate decarboxylase variant has the sequence number of 1 to 3. The glutamate decarboxylase variant is Escherichia coli, Lactobacillus, or Bacillus.