DRUG AND GENE DELIVERY CARRIER BASED ON SILICA NANOTUBE AND THE MANUFACTURING METHOD FOR THE SAME DELIVERY CARRIER

摘要

According to an embodiment of the present invention, since the plug of the silica nanotube is constituted by a ring-shaped primary plug and a secondary plug made of biomolecules having a thiol group, the drug or gene can be released in response to external stimuli in vivo They are useful as drugs and gene carriers. To this end, in particular, one embodiment of the present invention includes a silica nanotube which can carry a drug or a dielectric therein and has an opening formed at one end thereof; A ring-shaped primary plug formed of a metal nanomaterial around the opening; And a secondary cap formed from a biomolecule having at least one functional group selected from the group consisting of a thiol group, an imidazole group and a carboxyl group on the surface of the primary cap, and a gene transferable silica nanotube-based carrier do.