Centrifugal force-based microfluidic device for nucleic acid detection and microfluidic system comprising the device

摘要

target cells of a nucleic acid for detecting the centrifugal force-based microfluidic device and a microfluidic system is disclosed which comprises The. Microfluidic device according to the invention is a rotatable platform; Mixing a biological sample with a microfluidic structure that the fine particles trapped on the surface of the target cells within, disposed in the platform, separating the fine particles to a collecting and purifying the target cell, and irradiated to the fine particles from the outside of the platform target cell nucleic acid extraction unit for disrupting cells by using the electromagnetic wave; And the platform is disposed within the target cell the nucleic acid extraction unit with a nucleic acid polymerization solution in the microfluidic structure associated chain reaction (PCR) for the reaction mixture and mixed, and the mixed solution and the heat of the temperature control unit provided in the external platform comprises a polymerase chain reaction (PCR) unit for performing polymerase chain reaction (PCR) by thermal cycling through the exchange.