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An ultrasonic Petri dish and an ultrasonic monitoring system based on the same

机译:超声培养皿和基于该培养皿的超声监测系统

摘要

Petri dishes are used for ultrasound sonication experiment the reaction of cells or for cells to ultrasound, and Ultrasonic monitoring system is disclosed using the same. Ultrasound, which can hold a cell culture dishes and culture body; Characterized in that it comprises a; and is attached to the body ultrasonic sensing membrane that can detect the ultrasound signal. Ultrasonic culture plate body is made of a material having an acoustic impedance similar to living tissue, and low ultrasonic attenuation coefficient to reduce the damping effect increasing the efficiency of ultrasound transmission. Known as the piezoelectric film sensor is coated on both surfaces of the piezoelectric material, the electrode film is detected, and the inner bottom surface of the culture plate body, and the outer bottom surface, where at least one can be attached in the inner wall surface. Ultrasound monitoring system is attached to the culture dish ultrasonic ultrasonic sensing membrane; Ultrasound generating unit for irradiating an ultrasonic wave to the cell and culture medium contained in a culture plate ultrasound; Signal retrieving unit for retrieving the ultrasound detection signals detected by the film; The power of the ultrasonic waves to be irradiated to the cell and culture medium to analyze the signals received from the signal retrieving unit / strength / pressure, the height of the culture medium, the thickness of the cell layer, the culture medium / cavitation generated in the cell, the dynamic response of the cell, the temperature change of the culture medium / cell signal analysis unit for estimating the like; A display unit for outputting the result of analysis by the signal analyzer; And an ultrasonic generating unit, signal retrieving unit, a signal analysis unit, and a control unit for controlling the display section; characterized in that it comprises a ;
机译:培养皿用于超声超声处理实验或细胞对超声的反应,并公开了使用该培养皿的超声监测系统。超声波,可容纳细胞培养皿和培养体;其特征在于包括:并安装在可以检测超声信号的人体超声感应膜上。超声波培养板主体由具有与活体组织相似的声阻抗并且低的超声波衰减系数的材料制成,以减小阻尼效果,从而提高超声波传输的效率。在压电材料的两个表面上都涂有已知的压电膜传感器,检测电极膜,以及培养板体的内底表面和外底表面,其中至少一个可以附着在内壁上表面。超声监测系统安装在培养皿上超声超声传感膜上;超声波产生单元,用于向培养板超声波所包含的细胞和培养基照射超声波。信号获取单元,用于获取胶片检测到的超声检测信号;超声波辐射到细胞和培养基的功率,以分析从信号获取单元接收的信号/强度/压力,培养基的高度,细胞层的厚度,培养基/产生的空化在细胞中,细胞的动态响应,用于估计的培养基/细胞信号分析单元的温度变化等;显示单元,用于输出信号分析仪的分析结果;以及超声产生单元,信号获取单元,信号分析单元和用于控制显示部分的控制单元;特点是它包括一个;

著录项

  • 公开/公告号KR101441179B1

    专利类型

  • 公开/公告日2014-09-18

    原文格式PDF

  • 申请/专利权人

    申请/专利号KR20120022409

  • 申请日2012-03-05

  • 分类号C12M1/42;C12M1/22;C12N13/00;C12N5/071;

  • 国家 KR

  • 入库时间 2022-08-21 15:40:06

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