1. A method for evaluating the in vitro effector function of an antibody, which consists in incubating a three-dimensional spheroid or aggregate that contains tumor cells and natural killer cells with an antibody. The method according to claim 1, which consists in the following stages, in which: a) natural killer cells and tumor cells are mixed, b) approximately 10 cells per 200 μl are added to the wells of the multi-well plate, c) the multi-well plate is centrifuged and thereby inducing the formation of a three-dimensional spheroid or aggregate, d) add the antibody to the wells of the multi-well plate, e) incubate the multi-well plate for a period of about 20 to about 72 hours, e) analyze cells in the wells of the multi-well plate while using a cell sorter, and thereby the fluorescence excitation evaluated antitela.3 effector function. The method according to claim 2, characterized in that the natural killer cells are human natural killer cells. The method according to one of the preceding paragraphs, characterized in that the natural killer cells and tumor cells are mixed in a ratio of 10: 1 to 1: 10.5. The method according to claim 4, characterized in that the ratio is from 1: 2 to 1: 4.6. The method according to claim 2, characterized in that the incubation period is from about 20 to about 28 hours. The method according to claim 2 or 6, characterized in that the centrifugation is carried out at 1000 rpm for 10 minutes The method according to claim 2 or 6, characterized in that the tumor cell is a lymphoma cell. The method of claim 8, wherein the lymphoma cell is a Raji cell or SU-DHL4 cell, or Z138 cell. The method according to claim 2
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