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DRUG PREPARATION IN FORM OF ORALLY DISPERSIBLE TABLET AND METHOD FOR MAKING DRUG PREPARATION

机译:口服分散片形式的药物制备方法及药物制备方法

摘要

FIELD: medicine, pharmaceutics.;SUBSTANCE: invention refers to medicine and chemical-pharmaceutical industry, namely to drug preparations used in various spastic intestinal and pancreatic-biliary conditions, especially in irritable bowel syndrome, and to methods for making them. The drug preparation in the form of an orally dispersible tablet characterised by the fact that it contains a combination of hyoscine butyl bromide and diclofenac or its sodium salt in complex with polacrilin potassium in ratio of diclofenac or its sodium salt and polacrilin potassium of 1:2, and pharmaceutically acceptable additives containing mannitol, aspartame and crospovidone. Polyvinyl pyrrolidone K30, a flavouring agent and anhydrous colloidal silicon dioxide.;EFFECT: tablets have the improved bioavailability of the agent.;2 cl, 4 ex
机译:领域:药物和化学制药业,即用于各种痉挛性肠和胰胆疾病,特别是肠易激综合症的药物制剂及其制备方法。口服分散片剂形式的药物制剂,其特征在于它包含以二氯芬酸或其钠盐和波兰克里林钾为1:2的比例混合的hy碱丁基溴化物和双氯芬酸或其钠盐与泊洛克里林钾的复合物。 ,以及含有甘露醇,阿斯巴甜和交聚维酮的可药用添加剂。聚乙烯吡咯烷酮K30,一种调味剂和无水胶体二氧化硅。;效果:片剂具有改善的生物利用度。; 2 cl,4 ex

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