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DISPERSIBLE TABLET COMPRISING COATED DRUG-CONTAINING PARTICLES AND METHOD FOR THE PREPARATION THEREOF

机译:包含包衣药物颗粒的可分散片剂及其制备方法

摘要

The present invention relates to a dispersible tablet comprising a plurality of a coated drug-containing particles and a method for preparing said dispersible tablet. The inventive dispersible tablet comprising (a) a plurality of a drug-containing particle having a coating layer on the surface thereof; (b) a binding agent for protecting the coating layer; and (c) a pharmaceutically acceptable excipient, is capable of: maintaining a suitable hardness to prevent from the breakage thereof during the packing, circulating or storing period; enhancing the patient compliance through masking the drug bitterness; and disintegrating and dispersing rapidly enough to be easily administered to young children or old people having difficulty in swallowing a conventional oral formulation.
机译:本发明涉及一种包含多个包衣的含药物的颗粒的分散片剂及其制备方法。本发明的可分散片剂包含:(a)多个在其表面上具有涂层的含药物颗粒;和(b)用于保护涂层的粘合剂; (c)药学上可接受的赋形剂,能够:保持适当的硬度,以防止其在包装,循环或储存期间破裂。通过掩盖药物的苦味来增强患者的依从性;崩解和分散足够迅速,以易于吞咽常规口服制剂的幼儿或老年人服用。

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