DRUG PRODUCT, DRY POWDER INHALER, AND POLYFLUX COLLIDER ARRANGEMENT

摘要

PROBLEM TO BE SOLVED: To provide a polyflux collider arrangement for a dry powder dispenser capable of providing a higher fine particle fraction that can be targeted to the desired area of the lung and also capable of providing a higher total amount of drug that can be administered.SOLUTION: A polyflux collider arrangement that can be used in conjunction with a powder dispenser comprises a polyflux collider 32 having a body 30 at least partially encompassing a volume part and a single exit opening 42, the first inlet opening 44 and second inlet opening 46 and the exit opening being in communication with the encompassed volume part, and the exit opening being spaced from the reference plane. Upon inhalation of a dose, negative pressure is applied to the exit opening which causes a first stream of dry powder to be entrained from the first inlet opening into the encompassed volume part and directed toward the exit opening. The negative pressure also causes a second stream of dry powder to be entrained from the second inlet opening into the encompassed volume part and directed toward the exit opening.