PROBLEM TO BE SOLVED: To provide an agent which can improve skin function by promoting the formation of cornified envelope and tight junction.SOLUTION: This invention provides an epidermis-related factor activator that comprises at least one selected from carnitine and salt thereof, and carnitine derivative and salt thereof as an active ingredient, preferably an epidermis-related factor activator that comprises a compound represented by the general formula (1), where Rrepresents one of a 1-38C aliphatic hydrocarbon group, a hydrogen atom, and -COR, and Rrepresents a 1-37C aliphatic hydrocarbon group.
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