Omega-3 fatty acids or their alkyl esters, and oral administration for the pharmaceutical composition of the multi-layer coating forms, including statins

摘要

MULTILAYER-COATED PHARMACEUTICAL COMPOSITION CONTAINING OMEGA-3 FATTY ACID OR ALKYL ESTER THEREOF AND STATIN DRUG, IN PATTERN: (a) Gelatin containing omega-3 fatty acid or alkyl ester thereof A capsule core, (b) hydroxypropylmethylcellulose; and a 1: 2: 1 weight ratio copolymer of butyl methacrylate, (2-dimethylaminoethyl) methacrylate and methyl methacrylate are coated onto the gelatin capsule core to form. A pharmaceutical composition for oral administration comprising: a first coating layer; and (c) a second coating layer formed by coating a coating liquid containing a statin drug on the first coating layer.