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Composition for delivery of peptide YY and peptide YY agonist

机译:用于递送肽YY和肽YY激动剂的组合物

摘要

The present invention provides a composition (e.g., a pharmaceutical composition) comprising at least one delivery agent compound and at least one of peptide YY (PYY) and a PYY agonist. Preferably, the composition includes a therapeutically effective amount of peptide YY or the PYY agonist and the delivery agent compound. The composition of the present invention facilitates the delivery of PYY, a PYY agonist, or a mixture thereof and increases its bioavailability compared to administration without the delivery agent compound. PPY and PYY agonists possess activity as agents to reduce nutrient availability, including reduction of food intake.
机译:本发明提供了包含至少一种递送剂化合物和肽YY(PYY)和PYY激动剂中的至少一种的组合物(例如,药物组合物)。优选地,该组合物包括治疗有效量的肽YY或PYY激动剂和递送剂化合物。与不使用递送剂化合物的给药相比,本发明的组合物促进了PYY,PYY激动剂或其混合物的递送,并提高了其生物利用度。 PPY和PYY激动剂具有作为减少营养物供应(包括减少食物摄入)的作用。

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