Methods for evaluating the platelet reactivity of individuals treated with drug-eluting stent

摘要

The method of appraising the blood platelet reactivity of the individual which with medicine liquation characteristic sutento (DES) was processed is offered. First, the blood sample is obtained from the individual which was processed with DES and the P2Y12 antagonist. Consequently the blood sample, the particle which contains the adhesion GPIIb/IIIa receptor ligand, is mixed with adenosine two phosphoric acid (ADP), and professional star Glan gin E1 (PGE1). The said blend, constant temperature is left under the condition which is suited for the cohesion reaction of the particle, and, the blood platelet mediation cohesion reaction is rated in the said blend. The cohesion reaction being non- existence, or, decrease of the cohesion reaction, shows the fact that the individual which was processed with DES and the P2Y12 antagonist decreases blood platelet reactivity. The kit in order to appraise the obstruction of the blood platelet cohesion reaction and, the P2Y12 receptor antagonist which includes the GPIIb/IIIa receptor ligand which is fixed to the surface of the particle, adenosine two phosphoric acid (ADP), professional star Glan gin E1 (PGE1), with the anti- solidification medicine, and the buffer in order to maintain the blood which anti- it solidified was processed under the conditions which are suited for the blood platelet cohesion reaction, is offered.