首页>
外国专利>
PATHOGEN DETECTION BY STRAIN-SPECIFIC BACTERIAL RECOGNITION AND PLASMONIC AMPLIFICATION AND READOUT
PATHOGEN DETECTION BY STRAIN-SPECIFIC BACTERIAL RECOGNITION AND PLASMONIC AMPLIFICATION AND READOUT
展开▼
机译:应变特异性细菌识别和等离子扩增和读出检测病原菌
展开▼
页面导航
摘要
著录项
相似文献
摘要
The present invention relates to a method and kit for detecting bacteria in a sample. Substrate having a surface comprising an interdigitated Au electrode array and a plurality of siderophores specific to the bacteria and covalently attached to the surface. In one embodiment, the siderophore may contain a free OH (alcohol), amine, or carboxylic acid to which linker may be attached via ester (on the OH), amide (on the amine) or reverse the ester or amide using the siderophore carboxyl. The linker chain can then be short or long with and without heteroatom substitution to improve solubility as needed. The linker can terminate with a thiol which will react with a gold surface. Alternatively, the linker can terminate with another alcohol, amine or acid which can then be attached to corresponding functionality on the surface of choice.
展开▼