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Peptide derivatives for biofunctionalization of silicon substrates and their applications

机译:用于硅基板生物功能化的肽衍生物及其应用

摘要

The present invention relates to the use of a peptide consisting of 5 to 30 amino acid residues comprising an amino acid sequence selected from LLADTTHHRPWT (SEQ ID NO: 1), SPGLSLVSHMQT (SEQ ID NO: 2), and the sequences presenting at least 80% identity with SEQ ID NO: 1 or SEQ ID NO: 2, for the functionalization of silicon substrate. The present invention also relates to the specific peptides as such, and to silicon substrates functionalized by the adsorption on their surface of such specific peptides. Finally, the present invention is also directed to a process for the preparation of such functionalized silicon substrates, and to articles comprising a silicon substrate according to the invention.
机译:本发明涉及由5至30个氨基酸残基组成的肽的用途,所述氨基酸残基包含选自LLADTTHHRPWT(SEQ ID NO:1),SPGLSLVSHMQT(SEQ ID NO:2)的氨基酸序列,以及呈现至少80个氨基酸的序列与SEQ ID NO:1或SEQ ID NO:2的%同一性,用于硅底物的功能化。本发明还涉及这样的特定肽,并且涉及通过在这些特定肽的表面上的吸附而功能化的硅底物。最后,本发明还涉及制备这种官能化的硅基材的方法,并且涉及包含根据本发明的硅基材的制品。

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