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ALPHA-FORM ZINC-PHTHALOCYANINE NANOWIRES HAVING ENHANCED WATER SOLUBILITY AND WATER DISPERSIBILITY, COMPOSITE OF AN ALPHA-FORM ZINC-PHTHALOCYANINE NANOWIRE/PHENOTHIAZINE, AND METHOD FOR PREPARING SAME
ALPHA-FORM ZINC-PHTHALOCYANINE NANOWIRES HAVING ENHANCED WATER SOLUBILITY AND WATER DISPERSIBILITY, COMPOSITE OF AN ALPHA-FORM ZINC-PHTHALOCYANINE NANOWIRE/PHENOTHIAZINE, AND METHOD FOR PREPARING SAME
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机译:具有增强的水溶性和水不溶性的α型锌酞菁纳米线,α型锌酞菁纳米线/苯并噻嗪的复合物及其制备方法
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摘要
The present invention relates to alpha-form zinc-phthalocyanine nanowires (ZnPc NWs) having enhanced water solubility and water dispersibility, to a composite of an alpha-form zinc-phthalocyanine nanowire/phenothiazine, to a method for preparing same, and to a photosensitizer including same or a pharmaceutical composition including same for preventing or treating cancers. Since the alpha-form zinc-phthalocyanine nanowires or the composite of alpha-form zinc-phthalocyanine nanowire/phenothiazine according to the present invention exhibit dual traits, i.e., photothermal and photodynamic traits in single molecules, they are very useful for the development of a multifunctional molecular system and can also be usefully applied to light therapy of cancers due to their good light therapeutic effects. Also, the composite of alpha-form zinc-phthalocyanine nanowire/phenothiazine itself can exhibit fluorescence to facilitate the introduction of an imaging system, so that diagnosis and treatment can be simultaneously performed using a single substance.
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