Intra-articular Formulations and Methods for Treatment of Osteoarthritis

摘要

Intra-articular formulations and methods are provided for treating joint conditions, such as osteoarthritis. The formulations include an effective amount of recombinant human growth differentiation factor-5 (rhGDF-5) and an acidic vehicle, where the formulation is an intra-articular injection formulation. The formulations described herein can be used for treating joint conditions (e.g., osteoarthritis) via intra-articular injection in a subject in need thereof.