DIRECT MEASUREMENTS OF NANOPARTICLES AND VIRUS BY VIRUS MASS SPECTROMETRY

摘要

Apparatus and methods for performing mass spectrometry of a nanoparticle or virus analyte. Apparatus may include a laser desorption plate, a mass analyzer configured to measure mass over the range of m/z from 10⁵ to 10¹⁰, an electrical shield surrounding the mass analyzer, and a charge sensitive detector, wherein the laser firing is phase lock synchronized with the applied radiofrequency voltages.