Detecting Bacteria by Direct Counting of Structural Protein Units by the Integrated Virus Detection System (IVDS) and Mass Spectrometry

摘要

This report explores the direct counting of 'hair-like' structures specific for gram-positive bacteria. Indications show that these structures are intact after their removal from the cell and are sufficiently different from species to species of bacteria to indicate bacteria type if not actual identification. Their detection would represent a new approach to bacteria detection and identification. This report documents the detection of the bacterial structures using the physical nanometer counting methodology in the Integrated Virus Detection System (IVDS) and Electrospray Ionization-Mass Spectrometry.