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Modified live flavobacterium strains, stabilized vaccines comprising same, and methods of making and use thereof
Modified live flavobacterium strains, stabilized vaccines comprising same, and methods of making and use thereof
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机译:改良的活黄杆菌菌株,包含其的稳定疫苗及其制备和使用方法
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摘要
The present invention provides attenuated F. columnare strains that elicit an immune response in an animal, particularly a fish, against virulent F. columnare compositions comprising said strains, methods of vaccination against F. columnare, and kits for use with such methods and compositions. The invention further relates to a stabilization buffer, which allows the attenuated compositions to remain storage stable at ambient temperatures for extended periods of time.
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