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INHIBITORS OF ALPHA6 INTEGRIN/E-CADHERIN COMPLEX

机译:ALPHA6整合素/ E-钙粘蛋白复合物的抑制剂

摘要

In one aspect, the invention relates to an inhibitor of the α6 integrin/E-cadherin molecular complex for use as a medicament, in particular for the prevention or/and treatment of metastases of a primary cancer disease and a pharmaceutical composition or kit comprising as an active agent at least one of the inhibitors. In a further embodiment, the present invention relates to a method for determining the prognosis of metastatic homing of a primary cancer disease, in particular the aggressiveness of the metastatic potential of a primary cancer disease.
机译:一方面,本发明涉及α 6 整联蛋白/ E-钙粘蛋白分子复合物的抑制剂,其用作药物,特别是用于预防或/和治疗原发性癌症疾病的转移。药物组合物或药盒,其包含至少一种抑制剂作为活性剂。在另一个实施方案中,本发明涉及一种用于确定原发性癌症疾病的转移归巢的预后,尤其是原发性癌症疾病的转移潜能的侵袭性的方法。

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