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INHIBITORS OF ALPHA6 INTEGRIN/E-CADHERIN COMPLEX AND THEIR THERAPEUTIC AND DIAGNOSTIC USE IN CANCER
INHIBITORS OF ALPHA6 INTEGRIN/E-CADHERIN COMPLEX AND THEIR THERAPEUTIC AND DIAGNOSTIC USE IN CANCER
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机译:α6整合素/ E-钙粘蛋白复合物的抑制剂及其在癌症中的治疗和诊断用途
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摘要
In one aspect, the invention relates to an inhibitor of the α6 integrin/E- cadherin molecular complex for use as a medicament, in particular for the prevention or/and treatment of metastases of a primary cancer disease and a pharmaceutical composition or kit comprising as an active agent at least one of the inhibitors. In a further embodiment, the present invention relates to a method for determining the prognosis of metastatic homing of a primary cancer disease, in particular the aggressiveness of the metastatic potential of a primary cancer disease.
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